Is this PDRN ampoule vegan?

No. Centellian24 describes the PDRN Complex as containing salmon-extracted DNA, and the verified formula also includes hydrolyzed collagen. Those animal-derived ingredients make the finished ampoule unsuitable for a vegan routine. The product should not receive a vegan tag even though many other ingredients in the formula are plant-derived or synthetic.

Where does the ampoule go in a skincare routine?

Use it after cleansing and toner, before moisturizer. Spread a thin layer over the face and neck, then pat until absorbed. It can sit after lighter water-based serums if you use more than one step. Follow with moisturizer to finish the routine and apply sunscreen during the day because the formula contains retinol.

Do I need a Centellian24 Madeca device to use it?

No. The standard Centellian24 U.S. directions describe ordinary hand application after toner, followed by moisturizer. The global page suggests pairing the ampoule with a Madeca device for an enhanced routine, but the product remains a normal leave-on ampoule without it. Follow the device's own instructions separately if you choose to combine them.

Does PDRN Firming Boosting Ampoule feel sticky or heavy?

Centellian24 describes it as lightweight and fast absorbing, while exact-product users report a range from fluid and easy to layer to slightly sticky or rich. Amount and the products underneath can change the finish. Begin with a thin, even layer, pat rather than repeatedly rubbing and let it settle before adding moisturizer.

Can sensitive-feeling skin use this retinol ampoule?

An authorized exact-product listing says the finished ampoule passed a skin-irritation test, but that does not guarantee it will suit everyone. Retinol is present near the end of the formula, and one exact-product user still described slight irritation. Patch test first, introduce it gradually and pause if persistent discomfort develops. Sensitive skin is therefore not used as a guaranteed product filter here.

Can I layer it with another retinol product?

The ampoule already contains retinol, so count it as a retinol-containing step. If another product in your routine also uses retinol or a related retinoid, begin by alternating rather than layering both in the same session. Keep the rest of the routine simple, moisturize afterward and use sunscreen during the day.

Can oily or combination skin use this PDRN ampoule?

Combination skin appears in exact-product fit information, and some oily-dehydrated users like the ampoule's lighter feel. Others find it rich or slow to absorb. Start with less than you think you need, especially in humid weather or beneath makeup. Oily skin is not listed as a primary filter on this page because the finish is not uniformly weightless for every user.

Free standard shipping to eligible countries from €71

Centellian24

Centellian24 PDRN Firming Boosting Ampoule 30ml

Smoother look
Soft moisture
Easy layers
Ceramide care

Smoother look

Soft moisture

Easy layers

Ceramide care

PRODUCT DETAILS

Centellian24 PDRN Firming Boosting Ampoule is a 30ml leave-on serum for skin that looks less firm or feels short on bounce. Its lightweight, fast-absorbing texture goes after toner and before moisturizer, making the formula easy to layer in a morning or evening routine.

The formula pairs Sodium DNA—the label form behind the PDRN name—with niacinamide, Ceramide NP, hydrolyzed collagen, hydrolyzed elastin, adenosine, a peptide and retinol. Glycerin, trehalose and other humectants add surface moisture, while the conditioning blend helps skin feel smoother and more cushioned.

Choose it when your priorities are firmer-looking contours, a smoother appearance and comfortable moisture without a dense cream texture. A thin layer gives the cleanest finish; applying too much may feel richer or slightly tacky. Normal, dry, dehydrated and combination skin are the closest fit.

This formula is not vegan: Centellian24 identifies the PDRN as salmon-derived, and hydrolyzed collagen is also present. Retinol appears near the end of the ingredient list, so finish daytime use with sunscreen and keep expectations gradual rather than looking for an instant lift.

Learn more

GOES WELL WITH

Collagen gel mask Jericho rose jelly 35g 1ea€3.98

Collagen gel mask Sedum jelly 35g 1ea€4.00

COSRX Hyaluronic Acid Hydra Power Essence 100ml€15.98

COSRX Advanced Snail Hydrogel Eye Patch 60ea€18.88

COSRX Advanced Snail Peptide Eye Cream 25ml€17.88

HARUHARU WONDER Black Rice Bakuchiol Eye Cream 20ml€10.98

100 Reedle Shot Stick Pouch€7.88

1025 Dokdo Cleanser€10.99

A lightweight PDRN blend brings firming care, surface moisture and a smoother-looking finish to one easy daily layer.

Firmer-looking finish
Surface moisture
Barrier-supporting lipids
Easy daily layering

Key Ingredients

Seven rose and lilac glass lozenges form a loose sequence across a blush pedestal against a muted plum backdrop.

PDRN

A DNA-fragment skin conditioner commonly used to help skin look smoother, plumper and more resilient.

Overlapping ivory wax-like layers on a warm blush background, representing ceramide barrier lipids.

Ceramides

Barrier-supporting lipids that help reduce moisture loss and ease visible dryness.

Three open mauve, apricot and auburn grooves arc across one warm-ivory matte plaster surface beside a tiny coral point.

Retinol

May help soften the look of fine lines and uneven texture with consistent, carefully introduced leave-on use.

Centellian24 PDRN Firming Boosting Ampoule red glass dropper bottle against a pale gray background.

Concerns & Benefits

Your Concerns

1
Fine Lines And Wrinkles
Skin can look less smooth when fine creases become more noticeable around expressive areas.
2
Texture
Uneven surface texture can leave the complexion looking less refined and makeup less seamless.

How To Use

1After cleansing and toning, spread a thin, even layer over the face and neck. Pat until absorbed, then follow with moisturizer. Use morning or evening; finish daytime skincare with sunscreen.
2The formula already contains retinol. If your routine also includes another retinoid, begin by alternating rather than layering them in the same session. Apply less if the finish feels tacky. The optional Madeca device is not required for ordinary use. Avoid the immediate eye area, patch test before first use and stop if persistent discomfort develops.

Frequently asked questions

What is PDRN in Centellian24 PDRN Firming Boosting Ampoule?

PDRN is the name used for DNA-fragment ingredients in topical skincare. On this ingredient label, it appears as Sodium DNA. Centellian24 identifies the source as salmon-derived and pairs it with niacinamide, ceramide, retinol, hydrolyzed collagen, hydrolyzed elastin, adenosine and a peptide. Here it is part of a cosmetic ampoule for a firmer, smoother-looking finish, not a professional procedure.

Keep learning

Customer reviews

ABIB

Collagen gel mask Jericho rose jelly 35g 1ea

One ivory 35 g jelly sheet, set essence with no woven backing, named for the desert resurrection plant

€3.98

ABIB

Collagen gel mask Sedum jelly 35g 1ea

A pale-blue no-mesh hydrogel sheet built on eight declared hyaluronic acid forms, Jeju sedum extract and Palmitoyl Tripeptide-5

€4.00

COSRX

COSRX Hyaluronic Acid Hydra Power Essence 100ml

A simple oil-free gel essence with sodium hyaluronate, glycerin and panthenol for soft, smooth, comfortably hydrated skin.

€15.98

COSRX

COSRX Advanced Snail Hydrogel Eye Patch 60ea

Cooling two-size hydrogel patches that help tired under-eyes feel hydrated and look fresher in 20–30 minutes.

€18.88

COSRX

COSRX Advanced Snail Peptide Eye Cream 25ml

A lightweight airless-pump eye cream with snail secretion filtrate, niacinamide and five peptides for a softer, fresher-looking eye area.

€17.88

HARUHARU WONDER

HARUHARU WONDER Black Rice Bakuchiol Eye Cream 20ml

An unscented, milky bakuchiol eye cream for daily moisture and a smoother, brighter-looking eye area.

€10.98

VT COSMETICS

100 Reedle Shot Stick Pouch

A travel-size evening booster for smoother-feeling, more refined-looking skin.

2 mL × 10€7.88

ROUND LAB

1025 Dokdo Cleanser

Creamy, slightly acidic foam for a comfortable cleanse

150 ml€10.99

Centellian24 PDRN Firming Boosting Ampoule 30ml

Centellian24

Centellian24 PDRN Firming Boosting Ampoule 30ml

Smoother look
Soft moisture
Easy layers
Ceramide care

Smoother look

Soft moisture

Easy layers

Ceramide care

PRODUCT DETAILS

Learn more

GOES WELL WITH

Collagen gel mask Jericho rose jelly 35g 1ea€3.98

Collagen gel mask Sedum jelly 35g 1ea€4.00

COSRX Hyaluronic Acid Hydra Power Essence 100ml€15.98

COSRX Advanced Snail Hydrogel Eye Patch 60ea€18.88

COSRX Advanced Snail Peptide Eye Cream 25ml€17.88

HARUHARU WONDER Black Rice Bakuchiol Eye Cream 20ml€10.98

100 Reedle Shot Stick Pouch€7.88

1025 Dokdo Cleanser€10.99

A lightweight PDRN blend brings firming care, surface moisture and a smoother-looking finish to one easy daily layer.

Firmer-looking finish
Surface moisture
Barrier-supporting lipids
Easy daily layering

Key Ingredients