Is the serum lightweight, and does it feel sticky?

It has a lightweight, fast-absorbing texture and leaves skin looking plump and luminous without stickiness.

Which skin types is this serum listed for?

It is listed for combination, dry and oily skin. If your skin is sensitive or delicate, patch-test first and adjust use according to its response.

Does the formula contain retinol?

Yes, the formula contains retinol.

What happens to the sponge-derived spicules?

The hydrolyzed-sponge spicules naturally shed with dead skin over several days rather than being absorbed into the body.

Can I pair it with a Medicube AGE-R device?

If you are unfamiliar with spicule skincare, do not use this product with an AGE-R device.

Should I rinse it off?

No. Leave it on, then finish your routine with the recommended PDRN serum and cream or your usual water-based moisturizer.

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MEDICUBE

PDRN Pink Collagen Exosome Shot Ampoule 2000

What it is: A leave-on 2000-strength spicule serum for uneven tone, visible pores, elasticity and radiance, with a lightweight, nonsticky finish.

Tone & dark-spot care
Glass-glow visible pore care
Eight-form hydration support
Lightweight, nonsticky finish

Net weight: 30 ml

PDRN Pink Collagen Exosome Shot Ampoule 2000

30ml ·$18.99 USD

Tone & dark-spot care

Glass-glow visible pore care

Eight-form hydration support

Lightweight, nonsticky finish

Main active: PDRN
Intensity: Supportive

PRODUCT DETAILS

The MILD (2000) option is a leave-on spicule serum for uneven tone, dark spots, visible pores, elasticity and radiance. It has a lightweight, fast-absorbing and nonsticky finish that leaves skin looking plump and luminous.

Salmon PDRN gives the formula its dark-spot-care focus, while the exosome complex supports visible pore care and a glass-glow look. Ultra-low-molecular collagen rounds out the formula with elasticity and radiance care.

Eight forms of hyaluronic acid support intense hydration with a smoother, plumper-looking finish. The serum's natural pink hue comes from its ingredients rather than artificial coloring—a rosy detail with a clear reason behind it.

The spicule format can bring a noticeable tingle. Redness, itching or a warm sensation may also occur and can persist for some time, so pay attention to your skin's response, especially if it is sensitive or delicate. The formula also contains retinol, a useful detail to know as you find its place in your routine.

Learn more

GOES WELL WITH

100 Reedle Shot Stick Pouch$8.09 USD

1025 Dokdo Sun Cream$18.99 USD

Alpha-5 Mela Care Cream$14.99 USD

1025 Dokdo Cleanser$11.99 USD

1025 Dokdo Eye Cream$22.99 USD

1025 Dokdo Lotion$14.99 USD

1025 Dokdo Sleeping Pack$15.99 USD

All Around Safe Block Soft Finish Sun Milk SPF50+ PA+++$11.99 USD

Explore care for uneven tone, dehydration, visible pores and elasticity, with a lightweight, nonsticky finish.

Dark-spot care
Plump hydration
Visible pore care
Elasticity support

Key Ingredients

Seven rose and lilac glass lozenges form a loose sequence across a blush pedestal against a muted plum backdrop.

PDRN

A DNA-fragment skin conditioner commonly used to help skin look smoother, plumper and more resilient.

Lactobacillus Extracellular Vesicles and Milk Exosomes

A paired exosome complex used to support visible pore care and a glass-glow appearance.

A glossy translucent peach sculpture with flowing folded forms and small droplets, grounded by a soft shadow on a warm ivory backdrop.

Collagen Extract

An oil-soluble collagen extract used to help condition skin, support moisture retention, and leave the surface feeling smoother.

A cluster of translucent pale-aqua gel forms and clear glossy spheres rests on a softly lit blush-lilac surface, with scattered droplets and gentle shadows.

Eight-Form Hyaluronic Acid Complex

A blend of eight hyaluronic acid forms that helps replenish moisture for a soft, hydrated feel.

Niacinamide

Helps visibly brighten uneven tone and support the skin barrier.

Three open mauve, apricot and auburn grooves arc across one warm-ivory matte plaster surface beside a tiny coral point.

Retinol

May help soften the look of fine lines and uneven texture with consistent, carefully introduced leave-on use.

Panthenol

Pro-vitamin B5 that helps skin hold moisture and feel softer and more comfortable.

Close-up of a model with small translucent pink droplets arranged across one cheek.

Concerns & Benefits

Your Concerns

1
Dark Spots Hyperpigmentation
For visible dark spots that can leave your tone looking uneven.
2
Dehydration
For skin that feels short on moisture and could use a plumper-looking finish.

How To Use

1After cleansing, apply 2–3 drops over your entire face as the first skincare step, avoiding the areas near your eyes and lips.
2Gently rub the serum across your skin, then press with your hands to help it absorb.
3Leave the serum on; do not rinse it off.
4Follow with Medicube PDRN serum and cream, or finish with your usual water-based moisturizer. The formula is intended for daily use.

Model holding the pink pump bottle beside her cheek against a soft pink background.

Frequently asked questions

What might the spicule formula feel like?

Tingling can occur. Redness, itching or a heat sensation may also occur and can persist for some time.

Customer reviews

Frequently Bought Together

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This itemPDRN Pink Collagen Exosome Shot Ampoule 2000$18.99 USD

100 Reedle Shot Stick Pouch$8.09 USD

1025 Dokdo Sun Cream$18.99 USD

Total price: $46.07 USD

This itemPDRN Pink Collagen Exosome Shot Ampoule 2000$18.99 USD

100 Reedle Shot Stick Pouch$8.09 USD

1025 Dokdo Sun Cream$18.99 USD

Total price: $46.07 USD

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MEDICUBE PDRN Pink Collagen Exosome Shot 2000 | Sleepy Hello

MEDICUBE

PDRN Pink Collagen Exosome Shot Ampoule 2000

What it is: A leave-on 2000-strength spicule serum for uneven tone, visible pores, elasticity and radiance, with a lightweight, nonsticky finish.

Tone & dark-spot care
Glass-glow visible pore care
Eight-form hydration support
Lightweight, nonsticky finish

Net weight: 30 ml

PDRN Pink Collagen Exosome Shot Ampoule 2000

30ml ·$18.99 USD

Tone & dark-spot care

Glass-glow visible pore care

Eight-form hydration support

Lightweight, nonsticky finish

Main active: PDRN
Intensity: Supportive

PRODUCT DETAILS

Learn more

GOES WELL WITH

100 Reedle Shot Stick Pouch$8.09 USD

1025 Dokdo Sun Cream$18.99 USD

Alpha-5 Mela Care Cream$14.99 USD

1025 Dokdo Cleanser$11.99 USD

1025 Dokdo Eye Cream$22.99 USD

1025 Dokdo Lotion$14.99 USD

1025 Dokdo Sleeping Pack$15.99 USD

All Around Safe Block Soft Finish Sun Milk SPF50+ PA+++$11.99 USD

Explore care for uneven tone, dehydration, visible pores and elasticity, with a lightweight, nonsticky finish.

Dark-spot care
Plump hydration
Visible pore care
Elasticity support

Key Ingredients

PDRN

A DNA-fragment skin conditioner commonly used to help skin look smoother, plumper and more resilient.