Do I rinse it off after applying it?

No. Leave the serum on and apply your normal skincare afterward, finishing with a daily water-based moisturizer.

Is a tingling or prickly feeling expected?

Yes. The hydrolyzed-sponge micro-particles can create a prickly or tingling sensation. Temporary redness, itching or warmth may also occur, so adjust use according to your skin’s response.

What guidance does the brand give for sensitive skin?

MEDICUBE advises patch-testing first and adjusting use according to your skin’s response. The micro-particle formula can cause tingling and temporary redness, itching or warmth.

Can I apply it around my eyes or lips?

No. Apply it over the face while avoiding the eye, lip and mouth areas.

Can I use it with an AGE-R device?

MEDICUBE does not recommend pairing it with an AGE-R device if you’re unfamiliar with spicule-containing skincare.

What happens to the spicules after application?

MEDICUBE says the hydrolyzed-sponge spicules naturally shed with dead skin over several days rather than being absorbed into the body.

Does the 7500 formula contain retinol?

Yes. Retinol appears in the verified ingredient declaration for the 7500 serum.

Does “7500” mean it contains 7,500 ppm of PDRN, exosomes or collagen?

No. “7500” is the option name, not a verified concentration for those materials. The declaration lists Sodium DNA, identified as PDRN, at 10 ppm; Milk Exosome at 10 ppm; Collagen Extract at 10 ppm; and Lactobacillus Extracellular Vesicles at 50 ppm.

Free US Express shipping from $79

MEDICUBE

PDRN Pink Collagen Exosome Shot Ampoule 7500

What it is: An at-home, leave-on facial serum with hydrolyzed-sponge micro-particles for uneven-looking tone, visible pores, hydration and elasticity.

More even-looking tone
Hydration after one use
Smoother-looking texture after one use
More elastic-looking skin

Net weight: 30 ml

PDRN Pink Collagen Exosome Shot Ampoule 7500

30ml ·$20.99 USD

More even-looking tone

Hydration after one use

Smoother-looking texture after one use

More elastic-looking skin

Main active: PDRN
Intensity: Supportive

PRODUCT DETAILS

This is the STRONG 7500 option in MEDICUBE’s PDRN Pink Collagen Exosome Shot range; a MILD 2000 option is also available. The leave-on facial serum brings at-home care to routines focused on uneven-looking tone, visible pores, dark spots, brightening and elasticity. Its PDRN-and-exosome pairing supports more even, plumper-looking skin, while the collagen formula supports a more elastic, revitalized appearance.

Hydrolyzed-sponge spicules give the micro-particle serum its distinctive character and are intended to help prepare skin for the skincare that follows. A prickly or tingling sensation is expected. Temporary redness, itching or warmth may also occur, so use should be adjusted to your skin’s response.

There’s a softer detail, too: the serum’s pink hue comes naturally from its ingredients, without artificial coloring. Exact-product testing found improved hydration and texture after one use, along with an improvement in the appearance of hyperpigmentation after two weeks. It’s focused care for when you want a little more from your evening routine.

Learn more

GOES WELL WITH

2X TGG Care Hyaluronic HydroMask$19.99 USD

5 PDRN B5 Vital Soothing Toner$15.99 USD

5 PDRN Hyaluronic Acid Vital Hydrating Hydrogel Mask$12.99 USD

AC Fighting AHA BHA PHA Toner$9.99 USD

100 Reedle Shot Stick Pouch$8.09 USD

1025 Dokdo Sleeping Pack$15.99 USD

1025 Dokdo Cream$24.99 USD

1025 Dokdo Pad$20.99 USD

Focused support for a more hydrated, even, smooth and elastic-looking complexion.

More even-looking tone
Visible dark-spot care
A welcome hydration lift
Smoother-looking texture
Elasticity-focused care

Key Ingredients

Seven rose and lilac glass lozenges form a loose sequence across a blush pedestal against a muted plum backdrop.

PDRN

A DNA-fragment skin conditioner commonly used to help skin look smoother, plumper and more resilient.

Lactobacillus Extracellular Vesicles and Milk Exosome

Lactobacillus extracellular vesicles and milk exosome are skin-conditioning materials; finished-product benefits depend on the complete formula.

A cluster of translucent, pale peach pointed sculptural forms with small droplets, arranged on a warm ivory surface under soft directional light.

Hydrolyzed Sponge Spicules

Microscopic sponge-derived spicules that create a noticeable, stimulating feel in cosmetic formulas.

A glossy translucent peach sculpture with flowing folded forms and small droplets, grounded by a soft shadow on a warm ivory backdrop.

Collagen Extract

An oil-soluble collagen extract used to help condition skin, support moisture retention, and leave the surface feeling smoother.

Niacinamide

Helps visibly brighten uneven tone and support the skin barrier.

Clear hydrogel spheres and droplets on a pale lilac background.

Hyaluronic Acid

Helps hydrate and visibly plump the skin.

Three open mauve, apricot and auburn grooves arc across one warm-ivory matte plaster surface beside a tiny coral point.

Retinol

May help soften the look of fine lines and uneven texture with consistent, carefully introduced leave-on use.

Panthenol

Pro-vitamin B5 that helps skin hold moisture and feel softer and more comfortable.

A blush paper ribbon curves across an ivory platform with a pale lavender panel behind.

Peptides

Some exact peptide forms may support smoother, firmer-looking skin; evidence varies by peptide and formula.

Real Results

150.2%Improvement in skin hydration after one use^{1, 2}
4.3%Improvement in skin texture after one use^{1, 2}
17.5%Improvement in the appearance of hyperpigmentation after two weeks^{1, 2}
269%Increase in skin absorption rate 30 minutes after use^{1, 2}

Results published by MEDICUBE and Sabina. Individual results may vary.

Pink pump bottle surrounded by blue and pink spheres and radiating needle-like graphic lines.

Concerns & Benefits

Your Concerns

1
Uneven Skin Tone
When your complexion looks less even than you’d like.
2
Dark Spots Hyperpigmentation
When visible areas of discoloration make your tone look less uniform.

How To Use

1After evening cleansing, apply an appropriate amount over your face as your first skincare step once every three days, avoiding the eye, lip and mouth areas.
2Gently massage or press the serum into your skin until it absorbs.
3Leave it on, continue with your normal skincare and finish with a daily water-based moisturizer.

Two pink pump bottles on a reflective surface beside a pool of pink serum, with a droplet at one nozzle.

Frequently asked questions

When should I apply the 7500 serum, and how often should I use it?

Apply it after evening cleansing as your first skincare step once every three days. Massage or press it in until absorbed, then continue with your serum and moisturizer.

Keep learning

Customer reviews

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This itemPDRN Pink Collagen Exosome Shot Ampoule 7500$20.99 USD

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5 PDRN B5 Vital Soothing Toner$15.99 USD

Total price: $56.97 USD

This itemPDRN Pink Collagen Exosome Shot Ampoule 7500$20.99 USD

2X TGG Care Hyaluronic HydroMask$19.99 USD

5 PDRN B5 Vital Soothing Toner$15.99 USD

Total price: $56.97 USD

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MEDICUBE PDRN Pink Collagen Exosome Shot 7500 | Sleepy Hello

MEDICUBE

PDRN Pink Collagen Exosome Shot Ampoule 7500

What it is: An at-home, leave-on facial serum with hydrolyzed-sponge micro-particles for uneven-looking tone, visible pores, hydration and elasticity.

More even-looking tone
Hydration after one use
Smoother-looking texture after one use
More elastic-looking skin

Net weight: 30 ml

PDRN Pink Collagen Exosome Shot Ampoule 7500

30ml ·$20.99 USD

More even-looking tone

Hydration after one use

Smoother-looking texture after one use

More elastic-looking skin

Main active: PDRN
Intensity: Supportive

PRODUCT DETAILS

Learn more

GOES WELL WITH

2X TGG Care Hyaluronic HydroMask$19.99 USD

5 PDRN B5 Vital Soothing Toner$15.99 USD

5 PDRN Hyaluronic Acid Vital Hydrating Hydrogel Mask$12.99 USD

AC Fighting AHA BHA PHA Toner$9.99 USD

100 Reedle Shot Stick Pouch$8.09 USD

1025 Dokdo Sleeping Pack$15.99 USD

1025 Dokdo Cream$24.99 USD

1025 Dokdo Pad$20.99 USD

Focused support for a more hydrated, even, smooth and elastic-looking complexion.

More even-looking tone
Visible dark-spot care
A welcome hydration lift
Smoother-looking texture
Elasticity-focused care

Key Ingredients

PDRN

A DNA-fragment skin conditioner commonly used to help skin look smoother, plumper and more resilient.