Good night, glow. This concentrated, leave-on ampoule is made for your evening routine. It helps moisturize skin while improving the look of brightness and radiance overnight. Its cosmetic benefits also include a firmer, more elastic appearance, giving you overnight moisture and visible radiance alongside firmer-looking skin in one step.

At the center is 77.2% Extreme Biome™, a proprietary blend formulated with 10 probiotic and fermented ingredients. The formula's ferments go through a three-step fermentation method. Niacinamide supports the brighter-looking story, while panthenol, sodium hyaluronate, Ceramide NP with cholesterol, and adenosine add familiar hydration, barrier-care and smoothing context.

The 5X ampoule is a fifth-generation overnight treatment and the renewed version of the earlier Night Repair Probio Ampoule. Some retailers still keep “Probio” in the listing name. Missha recommends it for all skin types, making its moisture, radiance and visible-firmness focus available across normal, dry, oily, combination and sensitive skin routines.