How do I apply the cream?

Apply a moderate amount and gently massage it into the skin.

Is it suitable for acne-prone skin?

Yes. It is suitable for acne-prone skin and has been non-comedogenic tested.

How much azelaic acid, niacinamide, panthenol and Zinc PCA does it contain?

The formula contains 2% azelaic acid, 5% niacinamide, 1% panthenol and 3,000 ppm Zinc PCA.

What are the micro spicules in this cream?

They are marine-derived micro spicules used at 3,000 ppm and measuring 80–300 μm. They help improve the appearance of pores and uneven skin texture.

Does the formula include an ingredient aimed at supporting the skin barrier?

Yes. It contains 1% panthenol, included to help protect and support the skin barrier.

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Mary&May

Spicule Azelaic PDRN Spot Cream

What it is: A targeted spot cream for blemishes, clogged pores, uneven texture and the look of post-blemish marks.

Blemish and clogged-pore care
Gentle dead-skin exfoliation
Smoother-looking skin texture
Soothes redness and dull post-blemish marks

Net weight: 15g

Spicule Azelaic PDRN Spot Cream

15g ·$10.99 USD

Blemish and clogged-pore care

Gentle dead-skin exfoliation

Smoother-looking skin texture

Soothes redness and dull post-blemish marks

Main active: No primary active
Intensity: Supportive

PRODUCT DETAILS

Spicule Azelaic PDRN Spot Cream offers targeted care for blemishes, clogged pores and post-blemish marks. It brings exfoliating, texture-focused and soothing care together in one focused cream.

At the center is 2% azelaic acid, which gently exfoliates dead skin cells as part of its care for breakouts and lingering marks. The formula pairs it with 3,000 ppm marine-derived micro spicules to help improve the appearance of clogged pores and uneven skin texture.

CICA PDRN and 5% niacinamide help soothe the look of redness and improve dull post-blemish marks. Tea tree, 3,000 ppm Zinc PCA and madecassoside join azelaic acid in a blend intended to rebalance the look of skin affected by blemish concerns. The formula also includes 1% panthenol to support the skin barrier alongside this targeted care.

The cream is suitable for acne-prone skin and non-comedogenic tested. A primary skin irritation test has also been completed.

Learn more

GOES WELL WITH

1025 Dokdo Cream$24.99 USD

AC Clean Up Cleansing Foam$9.49 USD

100 Reedle Shot Stick Pouch$8.09 USD

1025 Dokdo Lotion$14.99 USD

1025 Dokdo Pad$20.99 USD

1025 Dokdo Sleeping Pack$15.99 USD

5α Control Clearing Cream$31.99 USD

A-Cica Calming Cream$25.99 USD

A focused mix of exfoliating, soothing and barrier-supporting care for blemishes, clogged pores, uneven texture and post-blemish marks.

Blemish-prone balance
Gentle exfoliating care
Smoother-looking texture
Softer-looking post-blemish marks
Barrier-minded comfort

Key Ingredients

Two shallow plaster wells are joined by a winding coral relief path with one small celadon accent.

Azelaic Acid

May support more even-looking post-blemish tone and calmer-looking skin in some formulas; results and tolerance depend on concentration, vehicle, and the complete formula.

A cluster of translucent, pale peach pointed sculptural forms with small droplets, arranged on a warm ivory surface under soft directional light.

Hydrolyzed Sponge Spicules

Microscopic sponge-derived spicules that create a noticeable, stimulating feel in cosmetic formulas.

Niacinamide

Helps visibly brighten uneven tone and support the skin barrier.

Abstract still life of intertwined pale sage and muted coral sculptural folds with clear droplets on a warm ivory surface.

Centella Asiatica and PDRN Complex

A pairing of Centella asiatica extract and PDRN that helps support a calmer-looking, soothed complexion.

Panthenol

Pro-vitamin B5 that helps skin hold moisture and feel softer and more comfortable.

A clear glass spoon holding pale powder, surrounded by translucent peach, blush and sage sculptural folds and glossy droplets on ivory.

Zinc PCA

A skin-conditioning zinc salt that supports light hydration while helping oily, blemish-prone skin look less shiny.

A small mound of fine white powder on a soft blush-lilac surface, photographed with diffused light and a gentle shadow.

Salicylic Acid

An exfoliating ingredient that may help rough-feeling skin look and feel smoother.

Silver and green tube floating on a mint background beside a trail of green droplets.

Concerns & Benefits

Your Concerns

1
Acne Blemishes
For visible blemishes and breakout-prone areas that could use focused care.
2
Blackheads Whiteheads
For clogged-looking pores and buildup from dead skin cells.

How To Use

1Apply a moderate amount and gently massage it into the skin.

Close-up of one tube dispensing a strand of green cream above a second open tube.

Frequently asked questions

What is this spot cream designed to help with?

It offers targeted care for blemishes, clogged pores and the appearance of post-blemish marks. Its azelaic acid also gently exfoliates dead skin cells.

Keep learning

Customer reviews

Frequently Bought Together

Buy these products together

This itemSpicule Azelaic PDRN Spot Cream$10.99 USD

1025 Dokdo Cream$24.99 USD

AC Clean Up Cleansing Foam$9.49 USD

Total price: $45.47 USD

This itemSpicule Azelaic PDRN Spot Cream$10.99 USD

1025 Dokdo Cream$24.99 USD

AC Clean Up Cleansing Foam$9.49 USD

Total price: $45.47 USD

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A gentle, low-pH foam for cleansing sebum and facial impurities

150 ml$9.49 USD

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100 Reedle Shot Stick Pouch

A travel-size evening booster for smoother-feeling, more refined-looking skin.

2 mL × 10$8.09 USD

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1025 Dokdo Lotion

A lightweight, unscented facial moisturizer with three forms of hyaluronic acid for lasting moisture without stickiness.

200 ml$14.99 USD

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1025 Dokdo Pad

Two-sided toner care for tidier texture and balanced moisture.

70 pads / 120 g$20.99 USD

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1025 Dokdo Sleeping Pack

A lightweight, unscented overnight gel for hydration and smoother-feeling skin.

100 ml$15.99 USD

DR CEURACLE

5α Control Clearing Cream

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Mary&May Spicule Azelaic PDRN Spot Cream | 15g

Mary&May

Spicule Azelaic PDRN Spot Cream

What it is: A targeted spot cream for blemishes, clogged pores, uneven texture and the look of post-blemish marks.

Blemish and clogged-pore care
Gentle dead-skin exfoliation
Smoother-looking skin texture
Soothes redness and dull post-blemish marks

Net weight: 15g

Spicule Azelaic PDRN Spot Cream

15g ·$10.99 USD

Blemish and clogged-pore care

Gentle dead-skin exfoliation

Smoother-looking skin texture

Soothes redness and dull post-blemish marks

Main active: No primary active
Intensity: Supportive

PRODUCT DETAILS

Spicule Azelaic PDRN Spot Cream offers targeted care for blemishes, clogged pores and post-blemish marks. It brings exfoliating, texture-focused and soothing care together in one focused cream.

The cream is suitable for acne-prone skin and non-comedogenic tested. A primary skin irritation test has also been completed.

Learn more

GOES WELL WITH

1025 Dokdo Cream$24.99 USD

AC Clean Up Cleansing Foam$9.49 USD

100 Reedle Shot Stick Pouch$8.09 USD

1025 Dokdo Lotion$14.99 USD

1025 Dokdo Pad$20.99 USD

1025 Dokdo Sleeping Pack$15.99 USD

5α Control Clearing Cream$31.99 USD

A-Cica Calming Cream$25.99 USD

A focused mix of exfoliating, soothing and barrier-supporting care for blemishes, clogged pores, uneven texture and post-blemish marks.

Blemish-prone balance
Gentle exfoliating care
Smoother-looking texture
Softer-looking post-blemish marks
Barrier-minded comfort